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Patient-specific Extravasation Dosimetry Using Uptake Probe Measurements

“With patient radiation safety in mind, we maintain that both diagnostic and therapeutic extravasation events should be identified and characterized. Severe extravasations affect the diagnostic or therapeutic quality of nuclear medicine procedures, and the unintended dose to tissue and skin may eventually be clinically significant. A dedicated radiopharmaceutical injection monitoring system can be used to improve the accuracy of dosimetry and assist in determining the need for patient follow-up.” Full Text

Findings: Unintentional exposure poses risk to nuclear medicine patients

Lucerno highlighted a peer-reviewed publication in the radiation safety journal Health Physics demonstrating that extravasations of routinely-used radiopharmaceuticals can cause unintended irradiation to patient tissue that “exceed well-established radiation protection and regulatory limits.” Press Release

Topical sensor metrics for 18F-FDG positron emission tomography dose extravasation

“Partial extravasation of a PET dose is readily detected and differentiated using TAC metrics and these metrics could provide deeper insight into the impact of partial extravasation on image quality or quantitation.” Full Text

2021 Omnibus Includes Nuclear Medicine Patient Safety, Transparency Provisions

Lucerno announced that the Fiscal Year 2021 Omnibus Appropriations Act includes critical language to protect the safety of nuclear medicine patients and enhance transparency within the American healthcare system. Press Release

Precision Prospectus: Limiting Variability in PET Interpretation

“Reproducible, quantitative standardized uptake value (SUV) results from FDG-PET scans are increasingly viewed as important in clinical oncology—both in routine clinical practice, as well as in clinical trials.” Full Text

Extravasation Reporting: The Scientific Case for Regulatory Change

“The studies in which I have been involved identified factors such as the tools used for the injection, the technique, and the experience of the technologist that influence the probability of extravasation, rather than any patient-specific factor.” Full Text

Carilion Clinic supports Lucerno’s NRC Petition

Carilion Clinic, a leader in patient-centered care and quality assurance for nuclear medicine patients, supports Lucerno’s NRC Petition: “Over the next decade, cancer patients will have access to revolutionary new nuclear medicine treatments that will fundamentally alter how cancer is diagnosed and treated. The NRC should not allow a 40-year-old misunderstanding of whether and why extravasations occur to hamper this progress.” Full Text

Detection of 18F-FDG Dose Leakage Using a Topical Device

“As part of routine monitoring of 18F-FDG PET administrations, an interesting case was identified that mimicked extravasation but represented dose leakage during infusion via an automatic injector. The Lara device provided a useful tool for more timely critical evaluation and problem solving, extending advantages to the patient and practice.” Full Text

2021 Appropriations Bills Enhance Nuclear Medicine Patient Safety, Transparency

Lucerno announced that Fiscal Year 2021 bills advanced this week by the House Appropriations Committee to the House floor include critical language to protect the safety of nuclear medicine patients and enhance transparency within the American healthcare system. Press Release

Topical Sensor for the Assessment of Injection Quality for 18F-FDG, 68Ga-PSMA and 68Ga-DOTATATE Positron Emission Tomography

“Topical monitoring and characterization of PET dose administration is possible and practical with the LARA device. Extravasation and partial extravasation of PET doses are not only readily detected but they are also preventable. The LARA device can provide the insights into variables that could eliminate extravasation as a cause of image quality or SUV accuracy issues.” Full Text

Petition for Rulemaking Calls on NRC to Prioritize Patient Safety, Transparency

Lucerno submitted a formal petition for rulemaking to the U.S. Nuclear Regulatory Commission, which calls on the agency to update a 1980 policy that allows nuclear medicine injection errors to remain hidden from patients, treating physicians, and NRC itself. Press Release

Hospitals shouldn’t be exempt from reporting faulty radioisotope injections

“…NRC is now re-evaluating the loophole that allows significant infiltrations to go unreported. Requiring reporting would be a small step for hospitals to implement but a big step toward improving patient care.” Full Text